Figure 4.

In vivo B lymphocyte proliferation in sheep infected with BLV mutant proviruses. Graphic representation of the proportions of B+ BrdU+ cells within the total B lymphocyte population (at days 3 and 7 post-injection) and the corresponding absolute numbers of B lymphocytes in sheep (n° 4538, 4541, 4543 and 4544) infected, respectively, with BLV mutants (IG4, CRX3, CRE and GP30). The BrdU was injected at days 14, 21, 28, 35, 42 and 52. The vertical line corresponds to the seroconversion day as determined by an immunodiffusion test.