|
SOM and K-means Analysis of Tat-upregulated genes at the G1/S phase.a |
||||
| Gene Ontology |
Accession # |
Gene Title |
Gene Symbol |
Unigene ID |
|
|
||||
| Transcription/ |
D83782 |
SREBP cleavage-activating protein |
SCAP |
Hs.437096 |
| DNA binding |
AC004770 |
fatty acid desaturase 3 |
FADS3 |
Hs.21765 |
| Enzymes |
Y08685 |
serine palmitoyltransferase, long chain base subunit 1 |
SPTLC1 |
Hs.90458 |
| D50840 |
UDP-glucose ceramide glucosyltransferase |
UGCG |
Hs.432605 |
|
| AF038961 |
mannose-P-dolichol utilization defect 1 |
MPDU1 |
Hs.95582 |
|
| U67368 |
exostoses (multiple) 2 |
EXT2 |
Hs.75334 |
|
| M22488 |
bone morphogenetic protein 1 |
BMP1 |
Hs.1274 |
|
| AF002668 |
degenerative spermatocyte homolog, lipid desaturase (Drosophila) |
DEGS |
Hs.299878 |
|
| AB016247 |
sterol-C5-desaturase-like |
SC5DL |
Hs.287749 |
|
| X15525 |
acid phosphatase 2, lysosomal |
ACP2 |
Hs.75589 |
|
| D13643 |
24-dehydrocholesterol reductase |
DHCR24 |
Hs.75616 |
|
| AF020543 |
palmitoyl-protein thioesterase 2 |
PPT2 |
Hs.332138 |
|
| AL050118 |
fatty acid desaturase 2 |
FADS2 |
Hs.388164 |
|
| M16424 |
beta-hexosaminidase A (alpha polypeptide) |
HEXA |
Hs.411157 |
|
| L13972 |
sialyltransferase 4A (beta-galactoside alpha-2,3-sialyltransferase) |
SIAT4A |
Hs.356036 |
|
|
|
||||
| Membrane/ |
D79206 |
syndecan 4 (amphiglycan, ryudocan) |
SDC4 |
Hs.252189 |
| Antigens |
M90683 |
HLA-G histocompatibility antigen, class I, G |
HLA-G |
Hs.512152 |
| X58536 |
major histocompatibility complex, class I, C & B |
HLA-C, B |
Hs.77961 |
|
| AF068227 |
ceroid-lipofuscinosis, neuronal 5 |
CLN5 |
Hs.30213 |
|
| U72515 |
putative protein similar to nessy (Drosophila) |
C3F |
Hs.530552 |
|
| X85116 |
stomatin |
STOM |
Hs.439776 |
|
| Z26317 |
desmoglein 2 |
DSG2 |
Hs.412597 |
|
| S90469 |
P450 (cytochrome) oxidoreductase |
POR |
Hs.354056 |
|
|
|
||||
| Receptors/Ligands |
U97519 |
podocalyxin-like |
PODXL |
Hs.16426 |
| AI263885 |
interleukin 27 receptor, alpha |
IL27RA |
Hs.132781 |
|
| U60805 |
oncostatin M receptor |
OSMR |
Hs.238648 |
|
| M63959 |
low density lipoprotein receptor-related protein associated protein 1 |
LRPAP1 |
Hs.75140 |
|
| L25931 |
lamin B receptor |
LBR |
Hs.435166 |
|
| X00588 |
epidermal growth factor receptor |
EGFR |
Hs.77432 |
|
| M25915 |
clusterin |
CLU |
Hs.436657 |
|
| X87949 |
heat shock 70 kDa protein 5 (glucose-regulated protein, 78 kDa) |
HSPA5 |
Hs.310769 |
|
|
|
||||
| Proteases |
AF032906 |
cathepsin Z |
CTSZ |
Hs.252549 |
| AB001928 |
cathepsin L2 |
CTSL2 |
Hs.87417 |
|
| Y00264 |
Amyloid beta (A4) precursor protein |
APP |
Hs.177486 |
|
|
|
||||
| Protein transport/Chaperone |
D83174 |
serine (or cysteine) proteinase inhibitor, clade H, member 1 |
SERPINH1 |
Hs.241579 |
| Z49835 |
glucose regulated protein, 58 kDa |
GRP58 |
Hs.110029 |
|
| X97335 |
A kinase (PRKA) anchor protein 1 |
AKAP1 |
Hs.78921 |
|
| X90872 |
gp25L2 protein |
HSGP25L2G |
Hs.279929 |
|
| D49489 |
thioredoxin domain containing 7 (protein disulfide isomerase) |
TXNDC7 |
Hs.212102 |
|
| AF013759 |
calumenin |
CALU |
Hs.7753 |
|
| AL008726 |
protective protein for beta-galactosidase (galactosialidosis) |
PPGB |
Hs.118126 |
|
| Z50022 |
pituitary tumor-transforming 1 interacting protein |
PTTG1IP |
Hs.369026 |
|
| AA487755 |
FK506 binding protein 9, 63 kDa |
FKBP9 |
Hs.497972 |
|
|
|
||||
| Ion channel/transporter |
U81800 |
solute carrier family 16, member 3 |
SLC16A3 |
Hs.386678 |
| M23114 |
ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 |
ATP2A2 |
Hs.374535 |
|
| J04027 |
ATPase, Ca++ transporting, plasma membrane 1 |
ATP2B1 |
Hs.20952 |
|
| AL049929 |
ATPase, H+ transporting, lysosomal accessory protein 2 |
ATP6AP2 |
Hs.183434 |
|
| AL096737 |
solute carrier family 5, member 6 |
SLC5A6 |
Hs.435735 |
|
|
|
||||
| Unknown/Other |
AF052159 |
protein tyrosine phosphatase-like, member b |
PTPLB |
Hs.5957 |
| D14658 |
KIAA0102 gene product |
KIAA0102 |
Hs.87095 |
|
| AI867349 |
nicastrin-like protein |
NICALIN |
Hs.24983 |
|
| AL031228 |
solute carrier family 39 (zinc transporter), member 7 |
SLC39A7 |
Hs.66776 |
|
| X57398 |
nodal modulator 1, 2, 3 |
NOMO1, 2, 3 |
Hs.429975 |
|
|
a Bolded genes indicate those genes upregulated at the G1/S transition (found using both SOM and k-means analyses) | ||||
Liang et al. Retrovirology 2005 2:20 doi:10.1186/1742-4690-2-20 |
||||