Figure 2.

Effect of CLDN-7 molecules upon infection of 293T cells by HIV_NL4-3. A) HIV_NL4-3 Env(-) virus infection of either CLDN-7²¹¹- or CLDN-7¹⁵⁸-modified 293T cells. In experiment 1, HIV Env(-) at 50 ng of p24 was used to infect 10⁴ cells in each well; in experiment 2, 10⁴ cells were infected by virus at 100 ng of p24. B) HIV_NL4-3 Env(+) virus infection of either CLDN-7²¹¹- or CLDN-7¹⁵⁸-modified 293T cells. Plasmid pCDNA3-transfected 293T cells were also used as a control.