This article is part of the supplement: 2005 International Meeting of The Institute of Human Virology
Poster presentation
Immunodominant Anti-Gag SLYNTVATL Responses in HIV-patients With More Than Five Years of HAART-induced Undetectable Plasma Viremia
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* Corresponding author: Snjezana Z Lepej Snjezana.Zidovec@Lepejbfm.hr
1 Division of Cellular Immunology, University Hospital for Infectious Diseases, Zagreb, Croatia
2 Department for Research and Development, Institute of Immunology, Zagreb, Croatia
3 Croatian Refferal Center for AIDS, University Hospital for Infectious Diseases, Zagreb, Croatia
Retrovirology 2005, 2(Suppl 1):P1 doi:10.1186/1742-4690-2-S1-P1
Published: 8 December 2005First paragraph (this article has no abstract)
HIV-specific CD8+ T-cells in the peripheral blood diminish in most patients after the initiation of highly active antiretroviral therapy (HAART). However, examples of de novo appearance of HIV-specific CD8+ T-cells in patients with long-term successful therapy have also been described. The aim of our study was to determine the frequency and absolute counts of Gag-specific CD8+ T-cells in the peripheral blood of HIV-patients with more than 5 years of treatment-induced undetectable viremia and compare it with non-symptomatic untreated chronically-infected persons.