Figure 7.

Overview of the different tat constructs. (A) The position of the various deletions and mutations, and a summery of the inactivated (-) or deleted (△) viral genes is shown. See the Materials and Methods section for construction details. (B) Sequence alignment of the different tat genes. The position of the Y26A mutation is indicated in bold. (C) Sequence alignment of the corresponding part of the rev gene. The rev startcodon overlaps the tat codon for Y47.