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Characterization of HIV-1 subtype C envelope glycoproteins from perinatally infected children with different courses of disease

Hong Zhang, Federico Hoffmann, Jun He, Xiang He, Chipepo Kankasa, John T West, Charles D Mitchell, Ruth M Ruprecht, Guillermo Orti and Charles Wood*

Retrovirology 2006, 3:73 doi:10.1186/1742-4690-3-73

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Genotypic and functional properties of early infant HIV-1 envelopes

Michael Kishko, Mohan Somasundaran, Frank Brewster, John L Sullivan, Paul R Clapham, Katherine Luzuriaga Retrovirology 2011, 8:67 (15 August 2011)

Abstract | Full text | PDF | PubMed | Editor’s summary

This study provides extensive characterization of the genotypic and functional properties of HIV-1 env shortly after transmission. We present the first detailed comparisons of the macrophage tropism of infant and maternal env variants and their sensitivity to Maraviroc, the only CCR5 antagonist approved for therapeutic use. These findings may have implications for improving approaches to prevent mother-to-child HIV-1 transmission.

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Exceptional molecular and coreceptor-requirement properties of molecular clones isolated from an Human Immunodeficiency Virus Type-1 subtype C infection

Prasanta K Dash, Nagadenahalli B Siddappa, Asokan Mangaiarkarasi, Aruna V Mahendarkar, Padmanabhan Roshan, Krishnamurthy Anand, Anita Mahadevan, Parthasarathy Satishchandra, Susarla K Shankar, Vinayaka R Prasad, Udaykumar Ranga Retrovirology 2008, 5:25 (7 March 2008)

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