Email updates

Keep up to date with the latest news and content from Retrovirology and BioMed Central.

This article is part of the supplement: 2006 International Meeting of The Institute of Human Virology

Open Access Poster presentation

Up-regulation of interferon-a/APOBEC3G signal pathway potently inactivates HIV-1 infectivity in resting CD4-T cells

Keyang Chen, Jialing Huang, Chune Zhang, Sophia Huang, Giuseppe Nunnari, Feng-xiang Wang, Xiangrong Tong, Ling Gao, Kristi Nikisher and Hui Zhang*

  • * Corresponding author: Hui Zhang

Author Affiliations

Center for Human Virology, Division of Infectious Diseases, Department of Medicine, Thomas Jefferson University, Philadelphia, Pennsylvania, 19107, USA

For all author emails, please log on.

Retrovirology 2006, 3(Suppl 1):P69  doi:10.1186/1742-4690-3-S1-P69

Published: 21 December 2006

First paragraph (this article has no abstract)

Interferon (IFN) system, including various IFNs and IFN-inducible gene products, is well known for its potent innate immunity against wide-range viruses. Recently, a family of cytidine deaminases, functioning as another innate immunity against retroviral infection, has been identified. However, its regulation remains largely unknown.