The silent defense: Micro-RNA directed defense against HIV-1 replication

doi:10.1186/1742-4690-4-26

Retrovirology

Volume 4

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Commentary

The silent defense: Micro-RNA directed defense against HIV-1 replication

Ajit Kumar

Department of Biochemistry & Molecular Biology, George Washington University, Washington, D.C, USA

author email corresponding author email

Retrovirology 2007, 4:26doi:10.1186/1742-4690-4-26


Published:	12 April 2007

Abstract

MicroRNAs play critical role in regulating gene expression. MicroRNA profile of particular cell type bears the signature of cell type specific gene expression. Given that viral pathogens replicate by evading host defenses, research is now focused on the miRNA-regulated genes that critically regulate HIV-1 propagation in human host cells.