Retrovirology

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Open Access Research

Expression pattern analysis of transcribed HERV sequences is complicated by ex vivo recombination

Aline Flockerzi1, Jochen Maydt2, Oliver Frank3, Alessia Ruggieri1, Esther Maldener1, Wolfgang Seifarth3, Patrik Medstrand4, Thomas Lengauer2, Andreas Meyerhans5, Christine Leib-Mösch3,6, Eckart Meese1 and Jens Mayer1*

Author Affiliations

1 Department of Human Genetics, Medical Faculty, University of Saarland, Homburg, Germany

2 Max Planck-Institute for Informatics, Saarbruecken, Germany

3 Medical Faculty Mannheim of the Ruprecht-Karls, University of Heidelberg, Germany

4 Department of Experimental Medical Sciences, Lund University, Lund, Sweden

5 Institute of Virology, Medical Faculty, University of Saarland, Homburg, Germany

6 GSF – National Research Center for Environment and Health, Institute of Molecular Virology, Neuherberg, Germany

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Retrovirology 2007, 4:39 doi:10.1186/1742-4690-4-39

Published: 6 June 2007

Additional files

Additional file 1:

Additional information for HERV-KX sequence analysis. Additional information on analysis of HERV-KX sequences, including. (i) recombination analysis of HERV-KX sequences with RECCO, (ii) description of treatment of gaps in RECCO analysis, (iii) original RECCO output for HERV-KX sequences "B270", "93" and "94", (iv) multiple alignment of HERV-KX and HML-2 reference sequences, (v) reproduction of HERV-K(HML-2) gag sequence recombinants

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