Retrovirology

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The control of viral infection by tripartite motif proteins and cyclophilin A

Greg J Towers

Retrovirology 2007, 4:40 doi:10.1186/1742-4690-4-40

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BioMed Central: 14 citations

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Interplay between HIV Entry and Transportin-SR2 Dependency

Wannes Thys, Stéphanie De Houwer, Jonas Demeulemeester, Oliver Taltynov, Renée Vancraenenbroeck, Melanie Gérard, Jan De Rijck, Rik Gijsbers, Frauke Christ, Zeger Debyser Retrovirology 2011, 8:7 (30 January 2011)

Analysis of viral specificity reveals that TRN-SR2 is not used to the same extent by all lentiviruses. The DNA flap does not determine the TRN-SR2 requirement of HIV-1. The HIV-1 N74D capsid mutant is independent of TRN-SR2 when pseudotyped with the vesicular stomatitis virus glycoprotein (VSV-G). The dependency on TRN-SR2 is lost when the HIV N74D capsid mutant is pseudotyped with envelopes mediating pH-dependent endocytosis, such as the VSV-G and Ebola virus envelopes.

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A single amino acid substitution of the human immunodeficiency virus type 1 capsid protein affects viral sensitivity to TRIM5α

Ayumu Kuroishi, Katarzyna Bozek, Tatsuo Shioda, Emi E Nakayama Retrovirology 2010, 7:58 (7 July 2010)

By long-term cultivation of human CEMss cells infected with NL-4/5S6/7SvifS, the impaired replicative capability of the virus in human cells was rescued. Sequence analysis of the CA region of the adapted virus revealed a G-to-E substitution at the 116th position of the CA (G116E). Introduction of this substitution into the molecular DNA clone of NL-4/5S6/7SvifS indeed improved the virus' replicative capability in human cells.

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The macrophage in HIV-1 infection: From activation to deactivation?

Georges Herbein, Audrey Varin Retrovirology 2010, 7:33 (9 April 2010)

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Quantitative TaqMan® real-time PCR assays for gene expression normalisation in feline tissues

Yvonne Kessler, A Katrin Helfer-Hungerbuehler, Valentino Cattori, Marina L Meli, Bigna Zellweger, Pete Ossent, Barbara Riond, Claudia E Reusch, Hans Lutz, Regina Hofmann-Lehmann BMC Molecular Biology 2009, 10:106 (11 December 2009)

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Molecular control of HIV-1 postintegration latency: implications for the development of new therapeutic strategies

Laurence Colin, Carine Van Lint Retrovirology 2009, 6:111 (4 December 2009)

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TRIM5α and TRIMCyp form apparent hexamers and their multimeric state is not affected by exposure to restriction-sensitive viruses or by treatment with pharmacological inhibitors

Marie-Édith Nepveu-Traversy, Julie Bérubé, Lionel Berthoux Retrovirology 2009, 6:100 (3 November 2009)

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Human cellular restriction factors that target HIV-1 replication

Klaus Strebel, Jeremy Luban, Kuan-Teh Jeang BMC Medicine 2009, 7:48 (16 September 2009)

Although different host cell factors act to inhibit viral replication and limit infection, HIV-1 has a number of measures to counteract this function; Strebel, Luban and Jeang review our current understanding of these interactions.

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Modification of a loop sequence between α-helices 6 and 7 of virus capsid (CA) protein in a human immunodeficiency virus type 1 (HIV-1) derivative that has simian immunodeficiency virus (SIVmac239) vif and CA α-helices 4 and 5 loop improves replication in cynomolgus monkey cells

Ayumu Kuroishi, Akatsuki Saito, Yasuhiro Shingai, Tatsuo Shioda, Masako Nomaguchi, Akio Adachi, Hirofumi Akari, Emi E Nakayama Retrovirology 2009, 6:70 (3 August 2009)

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Modulation of HIV-1 infectivity and cyclophilin A-dependence by Gag sequence and target cell type

Saori Matsuoka, Elisabeth Dam, Denise Lecossier, François Clavel, Allan J Hance Retrovirology 2009, 6:21 (2 March 2009)

Research article   Open Access

Influence of vector design and host cell on the mechanism of recombination and emergence of mutant subpopulations of replicating retroviral vectors

Matthias Paar, Dieter Klein, Brian Salmons, Walter H Günzburg, Matthias Renner, Daniel Portsmouth BMC Molecular Biology 2009, 10:8 (9 February 2009)

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MDM2 is a novel E3 ligase for HIV-1 Vif

Taisuke Izumi, Akifumi Takaori-Kondo, Kotaro Shirakawa, Hiroaki Higashitsuji, Katsuhiko Itoh, Katsuhiro Io, Masashi Matsui, Kazuhiro Iwai, Hiroshi Kondoh, Toshihiro Sato, Mitsunori Tomonaga, Satoru Ikeda, Hirofumi Akari, Yoshio Koyanagi, Jun Fujita, Takashi Uchiyama Retrovirology 2009, 6:1 (7 January 2009)

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25 years of HIV-1 research – progress and perspectives

Mark A Wainberg, Kuan-Teh Jeang BMC Medicine 2008, 6:31 (31 October 2008)

25 years after the isolation of the human immunodeficiency virus, Mark Wainberg and Kuan-Teh Jeang highlight the achievements in HIV research and reflect on future challenges in the field.

Research article   Open Access

Gene expression analyses in Atlantic salmon challenged with infectious salmon anemia virus reveal differences between individuals with early, intermediate and late mortality

Sven Jørgensen, Sergey Afanasyev, Aleksei Krasnov BMC Genomics 2008, 9:179 (18 April 2008)

Research   Open Access

Both TRIM5α and TRIMCyp have only weak antiviral activity in canine D17 cells

Julie Bérubé, Amélie Bouchard, Lionel Berthoux Retrovirology 2007, 4:68 (24 September 2007)