Retrovirology

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Nuclear Factor 90(NF90) targeted to TAR RNA inhibits transcriptional activation of HIV-1

Emmanuel T Agbottah, Christine Traviss, James McArdle, Sambhav Karki, Georges C St Laurent and Ajit Kumar*

  • * Corresponding author: Ajit Kumar akumar@gwu.edu

  • † Equal contributors

Retrovirology 2007, 4:41 doi:10.1186/1742-4690-4-41

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Characterization of the HIV-1 RNA associated proteome identifies Matrin 3 as a nuclear cofactor of Rev function

Anna Kula, Jessica Guerra, Anna Knezevich, Danijela Kleva, Michael P Myers, Alessandro Marcello Retrovirology 2011, 8:60 (20 July 2011)

In this work we exploited a novel proteomic method to identify MATR3 as a cellular cofactor of Rev activity. MATR3 binds viral RNA and is required for the Rev/RRE mediated nuclear export of unspliced HIV-1 RNAs.

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Inhibition of HIV-1 replication by small interfering RNAs directed against Glioma Pathogenesis Related Protein (GliPR) expression

Gianni Capalbo, Thea Müller-Kuller, Ursula Dietrich, Dieter Hoelzer, Oliver G Ottmann, Urban J Scheuring Retrovirology 2010, 7:26 (31 March 2010)

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Lysine methylation of HIV-1 Tat regulates transcriptional activity of the viral LTR

Rachel Van Duyne, Rebecca Easley, Weilin Wu, Reem Berro, Caitlin Pedati, Zachary Klase, Kylene Kehn-Hall, Elizabeth K Flynn, David E Symer, Fatah Kashanchi Retrovirology 2008, 5:40 (22 May 2008)