Nuclear Factor 90(NF90) targeted to TAR RNA inhibits transcriptional activation of HIV-1
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* Corresponding author: Ajit Kumar akumar@gwu.edu
- Equal contributors
Retrovirology 2007, 4:41 doi:10.1186/1742-4690-4-41
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Anna Kula, Jessica Guerra, Anna Knezevich, Danijela Kleva, Michael P Myers, Alessandro Marcello Retrovirology 2011, 8:60 (20 July 2011) In this work we exploited a novel proteomic method to identify MATR3 as a cellular cofactor of Rev activity. MATR3 binds viral RNA and is required for the Rev/RRE mediated nuclear export of unspliced HIV-1 RNAs.
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