Table 2 |
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|
Quantitative analysis of virus core morphology of NC mutant HIV-1 particles produced by HeLaP4 cells |
||||||||
|
Dense cone shape core |
Dense material in base of cone |
Round centered core |
Round displaced core |
Tubular core structure |
Two core structures or membrane* |
No defined core |
Diameter of particles |
|
|
|
||||||||
|
wt |
19 |
38 |
21 |
1 |
0 |
7 |
113 ± 4 |
|
|
H23C |
7 |
16 |
16 |
40,5 |
6 |
0 |
14,5 |
134 ± 14 |
|
H44C |
1 |
7 |
5 |
45 |
13 |
1 |
28 |
129 ± 14 |
|
H23-H44C |
0 |
0 |
13 |
16 |
23 |
15* |
33 |
96 ± 12 |
|
ΔZF1 |
6 |
16 |
15 |
39 |
4 |
0 |
20 |
131 ± 12 |
|
ΔZF2 |
1 |
8 |
3 |
62 |
6 |
2 |
17 |
ND |
|
ΔZF1-ZF2 |
1 |
0 |
11 |
23,5 |
13 |
22,5* |
29 |
101 ± 13 |
|
|
||||||||
|
Number of particles observed: 80 to 200. Numbers are expressed in % of total observed particles. |
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|
Grigorov et al. Retrovirology 2007 4:54 doi:10.1186/1742-4690-4-54 |
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