Retrovirology

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Open Access

Basal shuttle of NF-κB/IκBα in resting T lymphocytes regulates HIV-1 LTR dependent expression

Mayte Coiras, María R López-Huertas, Joaquín Rullas, Maria Mittelbrunn and José Alcamí*

Retrovirology 2007, 4:56 doi:10.1186/1742-4690-4-56

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Expression and reactivation of HIV in a chemokine induced model of HIV latency in primary resting CD4+ T cells

Suha Saleh, Fiona Wightman, Saumya Ramanayake, Marina Alexander, Nitasha Kumar, Gabriela Khoury, Cândida Pereira, Damian Purcell, Paul U Cameron, Sharon R Lewin Retrovirology 2011, 8:80 (12 October 2011)

This HIV latency model demonstrates viral integration and no spontaneous production of infectious virus, the detection of MS RNA in the nucleus only, and the induction of virus production with multiple activating stimuli.

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Molecular control of HIV-1 postintegration latency: implications for the development of new therapeutic strategies

Laurence Colin, Carine Van Lint Retrovirology 2009, 6:111 (4 December 2009)

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TLR2 and TLR4 triggering exerts contrasting effects with regard to HIV-1 infection of human dendritic cells and subsequent virus transfer to CD4+ T cells

Sandra Thibault, Rémi Fromentin, Mélanie R Tardif, Michel J Tremblay Retrovirology 2009, 6:42 (6 May 2009)

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Caspase-3-mediated cleavage of p65/RelA results in a carboxy-terminal fragment that inhibits IκBα and enhances HIV-1 replication in human T lymphocytes

Mayte Coiras, María López-Huertas, Elena Mateos, José Alcamí Retrovirology 2008, 5:109 (1 December 2008)