Retrovirology

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Pathogenicity and immunogenicity of attenuated, nef-deleted HIV-1 strains in vivo

Paul R Gorry*, Dale A McPhee, Erin Verity, Wayne B Dyer, Steven L Wesselingh, Jennifer Learmont, John S Sullivan, Michael Roche, John J Zaunders, Dana Gabuzda, Suzanne M Crowe, John Mills, Sharon R Lewin, Bruce J Brew, Anthony L Cunningham and Melissa J Churchill

Retrovirology 2007, 4:66 doi:10.1186/1742-4690-4-66

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Nef-mediated enhancement of cellular activation and human immunodeficiency virus type 1 replication in primary T cells is dependent on association with p21-activated kinase 2

Kevin C Olivieri, Joya Mukerji, Dana Gabuzda Retrovirology 2011, 8:64 (5 August 2011)

Nef-mediated enhancement of cellular activation and viral replication in primary T cells is dependent on PAK2 and on the strength of the activating stimuli, and correlates with the ability of Nef to associate with PAK2. PAK2 is likely to play a role in Nef-mediated enhancement of viral replication and immune activation in vivo.

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Determinants in HIV-1 Nef for enhancement of virus replication and depletion of CD4+ T lymphocytes in human lymphoid tissue ex vivo

Stefanie Homann, Nadine Tibroni, Ingo Baumann, Serkan Sertel, Oliver T Keppler, Oliver T Fackler Retrovirology 2009, 6:6 (15 January 2009)

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Human cellular microRNA hsa-miR-29a interferes with viral nef protein expression and HIV-1 replication

Jasmine K Ahluwalia, Sohrab Khan, Kartik Soni, Pratima Rawat, Ankit Gupta, Manoj Hariharan, Vinod Scaria, Mukesh Lalwani, Beena Pillai, Debashis Mitra, Samir K Brahmachari Retrovirology 2008, 5:117 (23 December 2008)

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Mechanisms of HIV non-progression; robust and sustained CD4+ T-cell proliferative responses to p24 antigen correlate with control of viraemia and lack of disease progression after long-term transfusion-acquired HIV-1 infection

Wayne B Dyer, John J Zaunders, Fang Yuan, Bin Wang, Jennifer C Learmont, Andrew F Geczy, Nitin K Saksena, Dale A McPhee, Paul R Gorry, John S Sullivan Retrovirology 2008, 5:112 (11 December 2008)

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HIV-1 Nef: at the crossroads

John L Foster, J Victor Garcia Retrovirology 2008, 5:84 (22 September 2008)

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Compartmentalization of the gut viral reservoir in HIV-1 infected patients

Guido van Marle, M John Gill, Dione Kolodka, Leah McManus, Tannika Grant, Deirdre L Church Retrovirology 2007, 4:87 (4 December 2007)