Small non-coding RNAs, mammalian cells, and viruses: regulatory interactions?

doi:10.1186/1742-4690-4-74

Retrovirology

Volume 4

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Commentary

Small non-coding RNAs, mammalian cells, and viruses: regulatory interactions?

Man Lung Yeung¹ , Monsef Benkirane² and Kuan-Teh Jeang¹

¹Molecular Virology Section, Laboratory of Molecular Microbiology National Institute of Allergy and Infectious Diseases, National Institutes of Health Bethesda, Maryland 20892-0460, USA

²Insitute de Genetique Humaine, Montpellier, France

author email corresponding author email

Retrovirology 2007, 4:74doi:10.1186/1742-4690-4-74


Published:	15 October 2007

Abstract

Recent findings suggest that mammalian cells can use small non-coding RNAs (ncRNA) to regulate physiological viral infections. Here, we comment on several lines of evidence that support this concept. We discuss how viruses may in turn protect, suppress, evade, modulate, or adapt to the host cell's ncRNA regulatory schema.