|
Resolution: standard / high Figure 3.
A potential foot print of an HIV-1 escape mutation from human miRNA-mediated selection. The HIV-1 sequence (bottom strand) shown in this figure is from the LTR of pNL4-3.
Good base pairing of this sequence with human miR-326 (top strand) is shown (current);
however, an even better base pairing (original?) is inferred if a putative APOBEC
-mediated "G" to "A" change is corrected.
Yeung et al. Retrovirology 2007 4:74 doi:10.1186/1742-4690-4-74 |