Retrovirology

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Human immunodeficiency virus integrase inhibitors efficiently suppress feline immunodeficiency virus replication in vitro and provide a rationale to redesign antiretroviral treatment for feline AIDS

Andrea Savarino*, Mauro Pistello, Daniela D'Ostilio, Elisa Zabogli, Fabiana Taglia, Fabiola Mancini, Stefania Ferro, Donatella Matteucci, Laura De Luca, Maria L Barreca, Alessandra Ciervo, Alba Chimirri, Massimo Ciccozzi and Mauro Bendinelli

Retrovirology 2007, 4:79 doi:10.1186/1742-4690-4-79

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Response of a simian immunodeficiency virus (SIVmac251) to raltegravir: a basis for a new treatment for simian AIDS and an animal model for studying lentiviral persistence during antiretroviral therapy

Mark G Lewis, Sandro Norelli, Matt Collins, Maria Barreca, Nunzio Iraci, Barbara Chirullo, Jake Yalley-Ogunro, Jack Greenhouse, Fausto Titti, Enrico Garaci, Andrea Savarino Retrovirology 2010, 7:21 (16 March 2010)

Abstract | Full text | PDF | PubMed | 1 comment | Editor’s summary

The integrase strand transfer inhibitor raltegravir effectively inhibits SIV replication and combined with existing antiretroviral drugs could represent a new generation of ART capable of clearing virus from the body.

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"Shock and kill" effects of class I-selective histone deacetylase inhibitors in combination with the glutathione synthesis inhibitor buthionine sulfoximine in cell line models for HIV-1 quiescence

Andrea Savarino, Antonello Mai, Sandro Norelli, Sary El Daker, Sergio Valente, Dante Rotili, Lucia Altucci, Anna Palamara, Enrico Garaci Retrovirology 2009, 6:52 (2 June 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

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