Commentary
Methylation: a regulator of HIV-1 replication?
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* Corresponding author: Kuan-Teh Jeang kj7e@nih.gov
Molecular Virology Section, Laboratory of Molecular Microbiology, NIAID, the National Institutes of Health, Bethesda, Maryland, 20892 USA
Retrovirology 2007, 4:9 doi:10.1186/1742-4690-4-9
Published: 2 February 2007Abstract
Recent characterizations of methyl transferases as regulators of cellular processes have spurred investigations into how methylation events might influence the HIV-1 life cycle. Emerging evidence suggests that protein-methylation can positively and negatively regulate HIV-1 replication. How DNA- and RNA- methylation might impact HIV-1 is also discussed.