Figure 1.

Expression levels of the MuLV gene and protein in ICR (n = 12), SAMR1 (n = 12) and SAMP8 (n = 10) brains. (A) Analysis of genetic expression level of the MuLV, Akv gene (605 bp), by RT-PCR in the brains of ICR, SAMR1, and SAMP8 mice. Levels of GAPDH served as a measure of sample concentration. (B) Densitometry analysis of Akv expression in A. *statistically significant difference (p < 0.01). (C) Analysis of protein expression levels of the MuLV, CAgag (30 kDa), by Western blot in the brains of ICR, SAMR1, and SAMP8 mice. 50 μg of brain homogenates were used. Levels of B-actin were used as a measure of sample concentration. (D) Densitometry analysis of CAgag expression in C. *statistically significant difference (p < 0.01).