Retrovirology

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MicroRNA profile changes in human immunodeficiency virus type 1 (HIV-1) seropositive individuals

Laurent Houzet, Man L Yeung, Valery de Lame, Dhara Desai, Stephen M Smith and Kuan-Teh Jeang*

Retrovirology 2008, 5:118 doi:10.1186/1742-4690-5-118

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Relationships of PBMC microRNA expression, plasma viral load, and CD4+ T-cell count in HIV-1-infected elite suppressors and viremic patients

Kenneth W Witwer, Andria K Watson, Joel N Blankson, Janice E Clements Retrovirology 2012, 9:5 (12 January 2012)

miRNA profiles, obtained using multiple acquisition, data processing, and analysis methods, distinguished ES and uninfected controls from viremic HIV-1-infected patients. For several miRNAs, however, ES and viremic patients shared similar expression patterns. Differentially expressed miRNAs included those with reported roles in HIV-1 latency (miR-29 family members, miRs -125b and -150). Others, such as miR-31 and miR-31*, had no previously reported connection with HIV-1 infection but were found here to differ significantly with uncontrolled HIV-1 replication.

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HIV-1 assembly in macrophages

Philippe Benaroch, Elisabeth Billard, Raphaƫl Gaudin, Michael Schindler, Mabel Jouve Retrovirology 2010, 7:29 (7 April 2010)

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Human cellular restriction factors that target HIV-1 replication

Klaus Strebel, Jeremy Luban, Kuan-Teh Jeang BMC Medicine 2009, 7:48 (16 September 2009)

Although different host cell factors act to inhibit viral replication and limit infection, HIV-1 has a number of measures to counteract this function; Strebel, Luban and Jeang review our current understanding of these interactions.

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siRNA and shRNA screens advance key understanding of host factors required for HIV-1 replication

Kin-Hang Kok, Ting Lei, Dong-Yan Jin Retrovirology 2009, 6:78 (27 August 2009)

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HIV-1 TAR miRNA protects against apoptosis by altering cellular gene expression

Zachary Klase, Rafael Winograd, Jeremiah Davis, Lawrence Carpio, Richard Hildreth, Mohammad Heydarian, Sidney Fu, Timothy McCaffrey, Eti Meiri, Mila Ayash-Rashkovsky, Shlomit Gilad, Zwi Bentwich, Fatah Kashanchi Retrovirology 2009, 6:18 (16 February 2009)