Retrovirology

official impact factor 5.24

Open Access Highly Access Commentary

Hitting HIV where it hides

Andrew I Dayton

Author Affiliations

Laboratory of Molecular Virology, Division of Emerging and Transfusion Transmitted Diseases, OBRR/CBER/FDA, HFM 315, 1401 Rockville Pike, Rockville, MD 20852-1448, USA

Retrovirology 2008, 5:15 doi:10.1186/1742-4690-5-15

Published: 1 February 2008

Abstract

The recent finding that inhibitors of PI3/Akt can sensitize HIV infected macrophages to oxidative stress-induced cell death suggest a potential new therapeutic approach to targeting HIV reservoirs.