Table 1

Amino acid variation at codons 40 and 43 in HIV-1 reverse transcriptase
Codon 40
 Number
 pct of mut
 pct of total
 Codon 43
 Number
 pct of mut
 pct of total
D
 732
 38.0%
 0.452%
 E
 4262
 38.1%
 2.631%
F
 541
 28.1%
 0.334%
 Q
 2444
 21.8%
 1.509%
E/D
 264
 13.7%
 0.163%
 N
 1516
 13.5%
 0.936%
K
 54
 2.8%
 0.033%
 K/E
 836
 7.5%
 0.516%
K/E
 53
 2.8%
 0.033%
 K/Q
 699
 6.2%
 0.432%
A
 50
 2.6%
 0.031%
 R
 379
 3.4%
 0.234%
E/Q
 33
 1.7%
 0.020%
 K/N
 333
 3.0%
 0.206%
E/G
 27
 1.4%
 0.017%
 K/R
 285
 2.5%
 0.176%
E/A
 27
 1.4%
 0.017%
 E/Q
 122
 1.1%
 0.075%
Q
 21
 1.1%
 0.013%
 K/D/N/E
 41
 0.4%
 0.025%
V
 21
 1.1%
 0.013%
 A
 37
 0.3%
 0.023%
V/F
 10
 0.5%
 0.006%
 T
 36
 0.3%
 0.022%
S/F
 10
 0.5%
 0.006%
 K/H/N/Q
 34
 0.3%
 0.021%
<10 examples
 81
 4.2%
 0.050%
 M
 33
 0.3%
 0.020%
K/T
 20
 0.2%
 0.012%
Total
 1924
 100.0%
 1.188%
 S
 19
 0.2%
 0.012%
N/H
 14
 0.1%
 0.009%




K/A/T/E
 10
 0.1%
 0.006%




<10 examples
 69
 0.6%
 0.043%








Total
 11189
 100.0%
 6.908%

In a total of 161974 sequences the amino acid variation at codons 40 and 43 in reverse transcriptase was determined. Shown are the percentages of the specified amino acid change of all mutations at that position (pct of mut) and in the total population (pct of total).

Huigen et al. Retrovirology 2008 5:20   doi:10.1186/1742-4690-5-20

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