Retrovirology Volume 5
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CommentaryAPOBEC3G encapsidation into HIV-1 virions: which RNA is it?Klaus Strebel and Mohammad A Khan  Laboratory of Molecular Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, 4/312, Bethesda, MD, 20892-0460, USA author email corresponding author email
Retrovirology 2008,
5:55doi:10.1186/1742-4690-5-55 Abstract
APOBEC3G is a cytidine deaminase with potent antiviral activity. The protein deaminates single-stranded DNA but is known to bind cellular and viral RNAs. There is increasing evidence that RNA binding of APOBEC3G is important for packaging into viral particles. However, there is no consensus yet on the type of RNA involved. |