Table 1

Overview of CycT1 mutants used in this study.
Regions
 Helix#
 Amino acid positions
 # of clones
 Activity in murine cells (*1)








>100%
 50–100%
 <50%
Region 1
 2
 58–65
 29
 4
 14
 11
Region 2
 2
 67–71
 26
 3
 10
 13
Region 3
 3
 88–91
 16
 2
 5
 9
Region 4
 3
 93–96
 16
 3
 11
 2
Region 5
 4
 104–108
 5
 0
 0
 5
Region 6
 5
 132–137
 3
 0
 1
 2
Region 7
 5
 139–143
 9
 0
 0
 9
Region 8
 5
 145–148
 2
 0
 0
 2
Region 9
 1'
 149–152
 9
 3
 4
 2
total

115
 15
 45
 55

*1: Tat transactivation obtained with wt human CycT1 is set as 100%

Jadlowsky et al. Retrovirology 2008 5:63   doi:10.1186/1742-4690-5-63

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