Figure 6.

Substitution of a single arginine residue with alanine yields an improved inhibitor. The syncytium inhibition activity of the peptides P^cr-400, P^BLV-391 and the derivative peptide P^BLV-R403A was examined. The percentage syncytium inhibition following co-incubation of cells with the peptides is shown. Syncytia were counted in 10 low-power light microscope fields. Data points show the mean ± SD of triplicate assays. The asters show the data points for which the p values were calculated (see main text).