Table 3 |
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Amino acid inter-species, inter-group, inter-subtype, and intra-subtype divergence among protease, RT, and integrase sequences |
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|
Divergence |
Protease |
RT |
Integrase |
|
|
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|
Inter-species |
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|
HIV-1 (789) vs HIV-2 (26) |
0.51 ± 0.03 |
0.40 ± 0.04 |
0.40 ± 0.02 |
|
Inter-group |
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|
group M (764) vs O (21) |
0.29 ± 0.02 |
0.22 ± 0.01 |
0.18 ± 0.01 |
|
group M (764) vs N (4) |
0.21 ± 0.02 |
0.14 ± 0.01 |
0.11 ± 0.01 |
|
group O (21) vs N (4) |
0.30 ± 0.02 |
0.21 ± 0.01 |
0.18 ± 0.01 |
|
Inter-subtype |
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|
Subtype A (71) vs B (145) |
0.11 ± 0.03 |
0.10 ± 0.01 |
0.07 ± 0.01 |
|
Subtype A (71) vs C (337) |
0.10 ± 0.03 |
0.09 ± 0.01 |
0.07 ± 0.01 |
|
Subtype B (145) vs C (337) |
0.11 ± 0.02 |
0.09 ± 0.01 |
0.07 ± 0.01 |
|
Intra-subtype |
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|
Subtype A (71) |
0.05 ± 0.02 |
0.07 ± 0.02 |
0.05 ± 0.01 |
|
Subtype B (145) |
0.07 ± 0.03 |
0.06 ± 0.01 |
0.05 ± 0.02 |
|
Subtype C (337) |
0.06 ± 0.03 |
0.06 ± 0.01 |
0.04 ± 0.01 |
|
|
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Divergence was defined as the mean proportion of amino acid difference between all sequence pairs. The number of sequences compared are within parentheses. |
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|
Rhee et al. Retrovirology 2008 5:74 doi:10.1186/1742-4690-5-74 |
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