Retrovirology

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The HTLV-1 Tax interactome

Mathieu Boxus, Jean-Claude Twizere, Sébastien Legros, Jean-François Dewulf, Richard Kettmann and Luc Willems*

Retrovirology 2008, 5:76 doi:10.1186/1742-4690-5-76

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BioMed Central: 12 citations

Commentary   Open Access

How the DNA damage response determines the fate of HTLV-1 Tax-expressing cells

Mathieu Boxus, Luc Willems Retrovirology 2012, 9:2 (5 January 2012)

How the Human T lymphotropic virus type 1 (HTLV-1) Tax protein stimulates proliferation while triggering cell cycle arrest and senescence remains puzzling. There is also a debate about the ability of Tax to activate or inhibit the DNA damage response. Here, it is discussed how to rationalize apparently conflicting observations.

Research   Open Access Highly Accessed

Tax gene expression and cell cycling but not cell death are selected during HTLV-1 infection in vivo

Linda Zane, David Sibon, Lionel Jeannin, Marc Zandecki, Marie-Hélène Delfau-Larue, Antoine Gessain, Olivier Gout, Christiane Pinatel, Agnès Lançon, Franck Mortreux, Eric Wattel Retrovirology 2010, 7:17 (11 March 2010)

Research article   Open Access

Co-infection by human immunodeficiency virus type 1 (HIV-1) and human T cell leukemia virus type 1 (HTLV-1): does immune activation lead to a faster progression to AIDS?

Eduardo Gudo, Nilesh B Bhatt, Dulce Bila, Celina Abreu, Amílcar Tanuri, Wilson Savino, Suse Silva-Barbosa, Ilesh V Jani BMC Infectious Diseases 2009, 9:211 (22 December 2009)

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Distinct functions of HTLV-1 Tax1 from HTLV-2 Tax2 contribute key roles to viral pathogenesis

Masaya Higuchi, Masahiro Fujii Retrovirology 2009, 6:117 (17 December 2009)

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The nuclear envelopathies and human diseases

Ya-Hui Chi, Zi-Jie Chen, Kuan-Teh Jeang Journal of Biomedical Science 2009, 16:96 (22 October 2009)

Research   Open Access Highly Accessed

Identification of a novel motif responsible for the distinctive transforming activity of human T-cell leukemia virus (HTLV) type 1 Tax1 protein from HTLV-2 Tax2

Toshiyuki Shoji, Masaya Higuchi, Rie Kondo, Masahiko Takahashi, Masayasu Oie, Yuetsu Tanaka, Yutaka Aoyagi, Masahiro Fujii Retrovirology 2009, 6:83 (17 September 2009)

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The 14th International Conference on Human Retrovirology: HTLV and related retroviruses (July 1–4, 2009; Salvador, Brazil)

Luc Willems Retrovirology 2009, 6:77 (17 August 2009)

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The HBZ gene, a key player in HTLV-1 pathogenesis

Masao Matsuoka, Patrick L Green Retrovirology 2009, 6:71 (3 August 2009)

Research   Open Access

Induction of p21CIP1/WAF1 expression by human T-lymphotropic virus type 1 Tax requires transcriptional activation and mRNA stabilization

Ling Zhang, Huijun Zhi, Meihong Liu, Yu-Liang Kuo, Chou-Zen Giam Retrovirology 2009, 6:35 (8 April 2009)

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Anti-adult T-cell leukemia/lymphoma effects of indole-3-carbinol

Yoshiaki Machijima, Chie Ishikawa, Shigeki Sawada, Taeko Okudaira, Jun-nosuke Uchihara, Yuetsu Tanaka, Naoya Taira, Naoki Mori Retrovirology 2009, 6:7 (16 January 2009)

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How HTLV-1 may subvert miRNAs for persistence and transformation

Amel B Bouzar, Luc Willems Retrovirology 2008, 5:101 (12 November 2008)

Research   Open Access

Physical and in silico approaches identify DNA-PK in a Tax DNA-damage response interactome

Emad Ramadan, Michael Ward, Xin Guo, Sarah S Durkin, Adam Sawyer, Marcelo Vilela, Christopher Osgood, Alex Pothen, Oliver J Semmes Retrovirology 2008, 5:92 (15 October 2008)