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Resolution: standard / high Figure 6.
Tat Bru (A), Tat Mal (B), and Tat Eli (C) 3D structures. Region I is depicted in red, region II (cysteine-rich region) in orange, region III in yellow, region IV (basic region) in green, region V in light blue, region VI (residues 73–86/87) in blue and for Tat Eli the extra C terminal residues are in pink. The three Tat structures displayed a similar folding characterized by a core region
composed of a part of region I with the highly conserved Trp 11 while the functional
region II, IV and V are well exposed to the solvent. The extra residues in the C-terminus
of Tat Eli protrude from a groove between the basic region and the cysteine-rich region
and are exposed to solvent.
Watkins et al. Retrovirology 2008 5:83 doi:10.1186/1742-4690-5-83 |