Table 2

Inhibition of HIV-1 mediated cell-cell fusion by gp41 MPR derived peptides


IC50g
(nM, Mean ± S.D.)

IC50
(nM, Mean ± S.D.)

N36
>1000
LZ
> 1000
P1
913 ± 13.6
P1 + LZ
923.4 ± 11.7
T20
78 ± 5.6
T20 + LZ
579 ± 3.5
P5
60 ± 2.
P5 + LZ
61 ± 1.5
P5L
90 ± 1.7
P7
560 ± 10.7

Note: Peptides P5L and P7 are recombinants the other chemically synthesized

Yu et al. Retrovirology 2008 5:93   doi:10.1186/1742-4690-5-93

Open Data