Table 2

Sensitivity, specificity, positive and negative predictive values and odds ratio for the anti-Env antibody LIPS test in diagnosing HAM/TSP

Comparisons

Sensitivity

Specificity

PPV

NPV

OR (95% CI)

> 100,000 LU

HAM/TSP vs ATLL & Asymp

81%

72%

75%

79%

11.1 (3.7–33.5)

HAM/TSP vs ATLL

88%

58%

75%

75%

10.5 (2.8–39.4)

HAM/TSP vs Asymp

91%

55%

75%

80%

12.0 (2.8–51.4)

> 200,000 LU

HAM/TSP vs ATLL & Asymp

85%

70%

70%

85%

13.1 (4.1–42.0)

HAM/TSP vs ATLL

90%

56%

70%

83%

11.7 (2.8–47.9)

HAM/TSP vs Asymp

93%

52%

70%

87%

15.2 (3.0–77.9)

Note. PPV, positive predictive value; NPV, negative predictive value; OR, Odds ratio; CI, confidence interval.

Burbelo et al. Retrovirology 2008 5:96   doi:10.1186/1742-4690-5-96