This article is part of the supplement: Fourth Dominique International Conference. Maternal chronic viral infections transmitted to infants: from mechanisms to prevention and careHIV-1 internalization in polarized human trophoblasts occurs through a peculiar endocytic pathwayCentre de Recherche en Infectiologie, Centre Hospitalier de l'Université Laval, and Département de Biologie médicale, Université Laval, Québec (QC), Canada
from Fourth Dominique Dormont International Conference. Host-Pathogen Interactions in Chronic Infections Retrovirology 2008, 5(Suppl 1):O5doi:10.1186/1742-4690-5-S1-O5
First paragraph (this article has no abstract)In human trophoblastic cells, a correlation between early endosomal trafficking of HIV-1 and virus infection was previously documented. However, if HIV-1 is massively internalized in these cells, the endocytic pathway(s) responsible for viral uptake is still undefined. |




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