A major susceptibility locus for HTLV-1 infection in childhood maps to chromosome 6q27

Sabine Plancoulaine¹^,2, Antoine Gessain², Patricia Tortevoye², Anne Boland-Auge³, Alexandre Vasilescu³, Fumihito Matsuda³ and Laurent Abel¹

¹U550, INSERM, Paris, France; Human Genetics of Infectious Diseases, Université Paris Descartes, Paris, France

²Unité d'Epidémiologie et Physiopathologie des Virus Oncogènes, Institut Pasteur, France

³Centre National de Génotypage, Evry, France

corresponding author email

from Fourth Dominique Dormont International Conference. Host-Pathogen Interactions in Chronic Infections
Paris, France. 13-15 December 2007

Retrovirology 2008, 5(Suppl 1):O6doi:10.1186/1742-4690-5-S1-O6


Published:	9 April 2008

First paragraph (this article has no abstract)

Human T-cell leukemia/lymphoma virus type 1 (HTLV-1) is a human oncoretrovirus causing adult T-cell leukemia/lymphoma (ATL) and chronic neuromyelopathy. We showed previously, by segregation analysis, that a dominant gene controls HTLV-1 infection through breast-feeding in children of African origin.