This article is part of the supplement: Fourth Dominique International Conference. Maternal chronic viral infections transmitted to infants: from mechanisms to prevention and care

Oral presentation

HCV-specific T-cell responses during acute Hepatitis C Virus infection in pregnancy

Jonathan Honegger¹, Mona Prasad², David Colombo², David Bowen¹ and Christopher Walker^1,3

¹Center for Vaccines and Immunity, The Research Institute at Nationwide Children's Hospital, Columbus, OH 43205, USA

²Department of Obstetrics and Gynecology, Ohio State University, Columbus, OH 43210, USA

³Department of Pediatrics, Ohio State University, Columbus, OH 43205, USA

corresponding author email

from Fourth Dominique Dormont International Conference. Host-Pathogen Interactions in Chronic Infections
Paris, France. 13-15 December 2007

Retrovirology 2008, 5(Suppl 1):O8doi:10.1186/1742-4690-5-S1-O8

Published:	9 April 2008

First paragraph (this article has no abstract)

While T-cell immune responses are recognized as important determinants of acute hepatitis C virus (HCV) infection outcome in non-pregnant adults, little is known about HCV-specific T-cell immunity during pregnancy or its impact on vertical transmission. Here we describe the temporal course of T-cell responses and HCV replication in a patient with acute HCV infection during pregnancy.