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HIV-1 TAR miRNA protects against apoptosis by altering cellular gene expression

Zachary Klase1, Rafael Winograd1, Jeremiah Davis1, Lawrence Carpio1, Richard Hildreth1, Mohammad Heydarian2, Sidney Fu2, Timothy McCaffrey2, Eti Meiri3, Mila Ayash-Rashkovsky3, Shlomit Gilad3, Zwi Bentwich3 and Fatah Kashanchi1*

Author Affiliations

1 The Department of Microbiology, Immunology and Tropical Medicine program, The George Washington University School of Medicine, Washington, District of Columbia 20037, USA

2 The Department of Biochemistry and Molecular Biology, The George Washington University School of Medicine, Washington, District of Columbia 20037, USA

3 Rosetta Genomics Ltd., Rehovot, Israel

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Retrovirology 2009, 6:18 doi:10.1186/1742-4690-6-18

Published: 16 February 2009

Additional files

Additional file 1:

Figure S1. Schematic representation of the interpretation of the microarray results.

Format: JPEG Size: 78KB Download file

Open Data

Additional file 2:

Supplemental file 2. Raw output data from miRanda analysis. TAR 5' miRNA sequence was used to search for targets within the genes indicated as down-regulated by the microarray.

Format: TXT Size: 34KB Download file

Open Data

Additional file 3:

Supplemental file 3. Raw output data from miRanda analysis. TAR 3' miRNA sequence was used to search for targets within the genes indicated as down-regulated by the microarray.

Format: TXT Size: 18KB Download file

Open Data