Retrovirology

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APOBEC3G mRNA expression in exposed seronegative and early stage HIV infected individuals decreases with removal of exposure and with disease progression

Joel A Vázquez-Pérez, Christopher E Ormsby, Ramón Hernández-Juan, Klintsy J Torres and Gustavo Reyes-Terán*

Retrovirology 2009, 6:23 doi:10.1186/1742-4690-6-23

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Increased APOBEC3G and APOBEC3F expression is associated with low viral load and prolonged survival in simian immunodeficiency virus infected rhesus monkeys

Bianka Mußil, Ulrike Sauermann, Dirk Motzkus, Christiane Stahl-Hennig, Sieghart Sopper Retrovirology 2011, 8:77 (28 September 2011)

Our findings suggest a protective effect of APOBEC3 for HIV and SIV in vivo and indicate regulation of APOBEC3 by interferon during early infection and by contribution of other, hitherto undefined factors at later disease stages.