Retrovirology

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Raltegravir, elvitegravir, and metoogravir: the birth of "me-too" HIV-1 integrase inhibitors

Erik Serrao, Srinivas Odde, Kavya Ramkumar and Nouri Neamati*

Retrovirology 2009, 6:25 doi:10.1186/1742-4690-6-25

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Response of a simian immunodeficiency virus (SIVmac251) to raltegravir: a basis for a new treatment for simian AIDS and an animal model for studying lentiviral persistence during antiretroviral therapy

Mark G Lewis, Sandro Norelli, Matt Collins, Maria Barreca, Nunzio Iraci, Barbara Chirullo, Jake Yalley-Ogunro, Jack Greenhouse, Fausto Titti, Enrico Garaci, Andrea Savarino Retrovirology 2010, 7:21 (16 March 2010)

The integrase strand transfer inhibitor raltegravir effectively inhibits SIV replication and combined with existing antiretroviral drugs could represent a new generation of ART capable of clearing virus from the body.

Correction   Open Access

Raltegravir, elvitegravir, and metoogravir: the birth of "me-too" HIV-1 integrase inhibitors

Erik Serrao, Srinivas Odde, Kavya Ramkumar, Nouri Neamati Retrovirology 2009, 6:33 (8 April 2009)