Table 1

Participating patients in sample donation to the HIV Research BioBank and the date of creation and the sample types donated and for each cohort.

Cohort

Creation's date

Sample Type

# of patients with samples in the BioBank

Adults^a)

3rd June 2004

Blood

2,865

LTNPs^b)

3rd June 2004

Blood

181

Rapid progressors^c)

7th February 2008

Blood

19

Non-regenerators^d)

5th February 2008

Blood

12

Recent infections^e)

90 days of HIV+

7th February 2008

Blood

13

180 days of HIV+

15

OLT-HIV^f)

24th January 2008

Blood, liver and spleen biopsies

21

a) Cohort of Adults (CoRIS): includes patients older than 13 with a confirmed diagnosis of HIV-infection that have not received prior antiretroviral treatment and are being seen for the first time in the participating center; b) Cohort of Long Term Non-Progresors (LTNP): includes patients who have T-lymphocyte counts > 500/μL and undetectable viremia for more than 10 years; c) Cohort of Rapid Progressors: includes patients whose CD4 levels have fallen below 300 in less than 3 years after seroconversion and with a window of less than 3 years between the last negative and first positive HIV test; d) Cohort of Lymphocyte Non-Regenerators: includes patients who began HAART with T-lymphocyte < 200/μL that remained under observation with high activity antiretroviral therapy (HAART) treatment during a period of at least 2 years during which the viremia was consistently undetectable. At the conclusion of the observation period, their CD4 values must not have reached the critical level of 250 cells/μl and e) Cohort of Recent Infection: patients with a documented date of seroconversion less than 6 months prior; f) Cohort of HIV-infected patients with organ liver transplant (OLT-HIV): includes HIV-infected patients that have received a liver transplant primarily as a consequence of hepatitis C virus (VHC) induced cirrhosis.

García-Merino et al. Retrovirology 2009 6:27   doi:10.1186/1742-4690-6-27