Table 1 |
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|
Animal Information and analysis using the acute HIV-1 infection model. |
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|
Animal Index -sample date |
viral load (copies/ml) |
Number of Sampled Sequences |
Divergence |
Diversity |
Variance |
Max. HD |
Sequence Identity |
Estimated days post infection (95% CIs) |
χ2goodness of fit P value |
|
|
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|
r00065-day4 |
18,600 |
31 |
0.016% |
0.033% |
0.027% |
2 |
87.1% |
14 [4–35] |
0.79 |
|
|
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|
r00065-day7 |
1,660,000 |
41 |
0.018% |
0.037% |
0.043% |
3 |
87.8% |
16 [6–34] |
0.52 |
|
|
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|
r00065-day11 |
90,800,000 |
50 |
0.013% |
0.025% |
0.022% |
2 |
90.0% |
11 [4–25] |
0.82 |
|
|
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|
r00065-day18 |
39,750,000 |
31 |
0.0081% |
0.016% |
0.015% |
2 |
93.5% |
7 [1–25] |
0.93 |
|
|
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|
r98018-day7 |
20,000 |
33 |
0.0077% |
0.015% |
0.014% |
2 |
93.9% |
7 [1–23] |
0.93 |
|
|
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|
r98018-day14 |
12,380,625 |
67 |
0.026% |
0.052% |
0.055% |
4 |
82.1% |
22 [12–37] |
0.70 |
|
|
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|
r98018-day21 |
1,391,000 |
69 |
0.016% |
0.033% |
0.057% |
5 |
91.3% |
14 [7–27] |
0.86 |
|
|
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|
Animal information including time of sampling, viral load, and number of nef sequences obtained. For each sample, we calculate divergence, diversity, variance, maximum HD, and sequence identity. Estimated days since infection with 95% confidence intervals and p-values were calculated via Maximum Likelihood method to fit a Poisson distribution to Hamming distance distribution from the founder strain and the goodness of fit through a Chi-Square statistic. |
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|
Bimber et al. Retrovirology 2009 6:57 doi:10.1186/1742-4690-6-57 |
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