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The utilization of humanized mouse models for the study of human retroviral infections

Rachel Van Duyne†, Caitlin Pedati†, Irene Guendel, Lawrence Carpio, Kylene Kehn-Hall, Mohammed Saifuddin and Fatah Kashanchi*

  • * Corresponding author: Fatah Kashanchi bcmfxk@gwumc.edu

  • † Equal contributors

Retrovirology 2009, 6:76 doi:10.1186/1742-4690-6-76

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The utility of the new generation of humanized mice to study HIV-1 infection: transmission, prevention, pathogenesis, and treatment

Bradford K Berges, Mark R Rowan Retrovirology 2011, 8:65 (11 August 2011)

Abstract | Full text | PDF | PubMed |  Editor’s summary

The purpose of this review is to summarize the findings reported to date on all new humanized mouse models (those transplanted human HSCs) in regards to HIV-1 sexual transmission, pathogenesis, anti-HIV-1 immune responses, viral evolution, pre- and post-exposure prophylaxis, and gene therapeutic strategies.

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Innate immune recognition and activation during HIV infection

Trine H Mogensen, Jesper Melchjorsen, Carsten S Larsen, Søren R Paludan Retrovirology 2010, 7:54 (22 June 2010)

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