Figure 1.

A timeline of humanized mouse model development and retroviral research. A highlight of the noteworthy events of humanized mouse model system development over the past 30 years. The bottom half of the timeline denotes the emergence of key humanized mouse models. The top half of the timeline denotes the application of the models to HIV-1 and HTLV-1 research. The area from 2005 to 2009 has been expanded to show the increase in retroviral development within a short time period.