Commentary
Towards a genetic AIDS vaccine
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* Corresponding author: Ben Berkhout b.berkhout@amc.uva.nl
Laboratory of Experimental Virology, Department of Medical Microbiology, Center for Infectious Diseases and Immunology Amsterdam (CINIMA), Academic Medical Center (AMC), University of Amsterdam, the Netherlands
Retrovirology 2009, 6:93 doi:10.1186/1742-4690-6-93
Published: 16 October 2009Abstract
We discuss a recent Nature Medicine publication by Philip Johnson and co-workers (Vector-mediated gene transfer engenders long-lived neutralizing activity and protection against SIV infection in monkeys. Nat. Med. 2009, 15: 901-906) in which an effective HIV-1 vaccine was designed that is based on gene therapy. The introduced gene produces an antibody-like immunoadhesin in the blood that neutralizes the virus.