Table 3 |
||
|
PTLV evolutionary rate and time-scale calculated with a Bayesian relaxed molecular clock using 1st + 2nd codon positions of concatenated gag-pol-env-tax genes and tax only1. |
||
|
Clade |
gag-pol-env-tax |
tax(630-bp) |
|
|
||
|
Mean Posterior Substitution Rate2 |
6.29 × 10-7 (3.29 × 10-7 - 9.53 × 10-7) |
5.36 × 10-7 (3.21 × 10-7 - 8.1 × 10-7) |
|
|
||
|
PTLV root |
323,887 (147,042 - 529,980) |
191,759 (88,914 - 299,436) |
|
MarB43/PTLV-1 |
102,708 (58,833 - 109,552) |
77,259 (45,899 - 118,645) |
|
PTLV-13 |
53,896 (38,355 - 76,651) |
49,211 (39,783 - 59,155) |
|
HTLV-4/PTLV-2 |
242,627 (77,653 - 305,591) |
110,122 (46,324 - 180,712) |
|
PTLV-2 |
107,191 (41,349 - 182,273) |
67,460 (29,660 - 111,773) |
|
STLV-2 |
42,350 (11,650 - 87,100) |
31,018 (8,744 - 56,742) |
|
HTLV-2 |
25,346 (14,419 - 40,104) |
20,982 (13,591 - 27,792) |
|
HTLV-2a, b4 |
21,492 (14,426 - 28,212) |
20,947 (13,703 - 27,783) |
|
PTLV-3 |
120,574 (52,894 - 201,260) |
75,795 (34,342 - 127,209) |
|
PTLV-3a/3b |
54,953 (26,648 - 102,445) |
41,524 (17,149 - 68,097) |
|
PTLV-3c/3d |
ND5 |
18,452 (4,386 - 36,666) |
|
PTLV-3d/3a+3b |
115,117 (52,822 - 200,926) |
ND |
|
|
||
|
1. The tMRCA is the median Bayesian estimate in years ago (ya); 95% HPD intervals are given in parentheses. ND = not determined. 2. Substitutions/site/year 3. The tMRCA for this node was constrained by using a uniform distribution prior of 40,000-60,000 ya. 4. The tMRCA for this node was constrained by using a uniform distribution prior of 15,000-30,000 ya. 5. The complete genome of STLV-3c is currently not available. |
||
|
Sintasath et al. Retrovirology 2009 6:97 doi:10.1186/1742-4690-6-97 |
||
