Retrovirology

official impact factor 5.24

This article is part of the supplement: AIDS Vaccine 2009

Open Access Oral presentation

S01-04 OA. Phenotypic analyses of CD8+ T cells that mediate virus inhibition from HIV-1 vaccinees and HIV-1+ virus controllers

SA Freel1*, PK Chattopadhyay2, L Lamoreaux3, D Zarkowsky3, RG Overman4, C Ochsenbauer-Jambor5, JC Kappes5, CK Cunningham6, TN Denny7, KJ Weinhold8, G Ferrari9, RA Koup3, BS Graham10, BF Haynes11, M Roederer2 and GD Tomaras12

  • * Corresponding author: SA Freel

Author Affiliations

1 DHVI and Surgery, Duke University Medical School, Durham, USA

2 ImmunoTechnology Section, Vaccine Research Center, NIAID, NIH, Bethesda, MD, USA

3 Immunology Core Section, Vaccine Research Center, NIAID, NIH, Bethesda, MD, USA

4 Duke University Medical Center; DHVI and Surgery, Durham, NC, USA

5 University of Alabama, Department of Medicine, Birmingham, AL, USA

6 Duke University Medical Center, Department of Pediatrics, Durham, NC, USA

7 Duke University Medical Center; DHVI and Medicine, Durham, NC, USA

8 Duke University Medical Center; DHVI, Immunology and Surgery, Durham, NC, USA

9 Duke University Medical Center; Department of Surgery, Durham, NC, USA

10 Viral Pathogenesis Laboratory; Vaccine Research Center, NIAID, NIH, Bethesda, MD, USA

11 Duke University Medical Center; DHVI, Immunology, and Medicine, Durham, NC, USA

12 Duke University Medical Center, DHVI, Surgery and Immunology, Durham, NC, USA

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Retrovirology 2009, 6(Suppl 3):O1 doi:10.1186/1742-4690-6-S3-O1

Published: 22 October 2009

First paragraph (this article has no abstract)

CD8-mediated virus inhibition can be detected in HIV-1+ subjects controlling virus replication in the absence of ART. Characterizing the CD8+ T cells that mediate virus inhibition is important for determining the nature of CD8+ T cells that need to be elicited by an HIV-1 vaccine.