This article is part of the supplement: AIDS Vaccine 2009
OA011-04. Striking elevations in systemic and mucosal cytokine and chemokine levels in acute HIV-1 infection
1 Jenner Institute, University of Oxford, Newbury, UK
2 Blood Systems Research Institute, San Francisco, CA, USA
3 SCHARP, Seattle, WA, USA
4 University of North Carolina, Durham, NC, USA
5 Duke University, Durham, USA
6 Jenner Institue, University of Oxford, Newbury, UK
Retrovirology 2009, 6(Suppl 3):O10 doi:10.1186/1742-4690-6-S3-O10
Published: 22 October 2009First paragraph (this article has no abstract)
Innate immune responses can be activated rapidly in response to infection and may contribute to control of early viral replication or conversely, mediate immunopathogenic effects. To gain insight into the nature and kinetics of the earliest cytokine responses activated in acute HIV-1 infection (AHI), we analysed changes in systemic and mucosal cytokine/chemokine levels during primary infection.