Table 2 |
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|
Neutralisation properties of different monoclonal antibodies against XMRV and MLV pseudotyped with three different envelopes. |
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|
Neutralisation of |
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|
Hybridoma1 |
Raised in |
Isotype |
XMRV |
MLV(X) |
Friend |
Moloney |
|
|
||||||
|
83A25' |
Rat |
IgG2A |
Y (88) |
Y (89) |
ND |
ND |
|
24-7 |
Mouse |
IgMK |
N |
N |
ND |
ND |
|
48 |
Mouse |
IgG2A |
N |
N |
Y (95) |
Y (83) |
|
538 |
Mouse |
IgM |
N |
N |
N |
Y (63) |
|
603 |
Mouse |
IgM |
N |
Y (96) |
N |
ND |
|
609 |
Mouse |
IgM |
Y (71) |
N |
ND |
ND |
|
610 |
Mouse |
IgM |
N |
Y (64) |
ND |
ND |
|
613 |
Mouse |
IgM |
N |
Y (91) |
ND |
ND |
|
615 |
Mouse |
IgM |
N |
N |
ND |
ND |
|
|
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|
Y indicates neutralisation; N indicates no neutralisation; ND is not determined The number in brackets refers to the percentage neutralisation at the least diluted antibody concentration. 1 See references [13] and [14] for description of hybridoma cell lines |
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|
Groom et al. Retrovirology 2010 7:10 doi:10.1186/1742-4690-7-10 |
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