Table 3

Neutralisation properties of different human sera against XMRV and MLV pseudotyped with three different envelopes.

Neutralisation of

Sample ID

XMRV

MLV(X)

Friend

VSV

XMRV detected by PCR


Barts and the London

Q488

+

-

-

-

ND

Q610

+

-

-

-

ND

Q663

+

ND

ND

ND

ND

St George's University of London

Q302

++

++

++

++

no

Q304

++

++

++

++

no

Q305

++

++

++

++

no

Q306

++

++

++

++

no

Q307

++

+

+

-

no

Q308

++

++

++

++

no

Q309

++

++

++

++

no

Q310

++

++

++

++

no

Q311

++

+

+

+

no

Q312

++

++

++

++

no

Q313

++

++

++

++

no

Q314

++

ND

ND

++

no

Q315

++

++

++

++

no

Q316

++

++

++

++

no

Q317

++

++

++

++

no

Q319

++

ND

ND

++

no

Q320

++

++

++

++

no

Q321

++

++

++

++

no

Q323

++

++

++

++

no

Q324

++

++

++

++

no

Q326

++

ND

ND

ND

no

Q372

+

-

-

+

no

Glasgow Calendonian University

Q125

+

++

++

-

ND


+ indicates neutralising activity; ++ indicates strong neutralising activity; - indicates no neutralising activity; ND is no determined.

Groom et al. Retrovirology 2010 7:10   doi:10.1186/1742-4690-7-10

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