Table 1

Summary of the ZAP mutants for their binding activities to the target RNA, the exosome, and the RNA helicase p72

Mutant

3

13

63

93

103

113

133

RNA binding

L

N

L

N

M

N

N

p72 helicase

N

N

M

M

N

N

L

Exosome

N

N

N

N

N

N

N

N: Normal; M: medium; L: low

Wang et al. Retrovirology 2010 7:19   doi:10.1186/1742-4690-7-19