Additional file 5.IFD binding mode of raltegravir at the SIVmac251 catalytic site in complex with proviral DNA. Molecular surfaces are shown for IN (gray), catalytic loop (residues 140-149; cyan), metal ions (magenta), 3'-DNA strand (green), and 5'-DNA strand (yellow). This figure was prepared using PyMOL [73]. Format: PNG Size: 657KB Download file Lewis et al. Retrovirology 2010 7:21 doi:10.1186/1742-4690-7-21 |