Interplay between HIV Entry and Transportin-SR2 Dependency
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* Corresponding author: Zeger Debyser zeger.debyser@med.kuleuven.be
Retrovirology 2011, 8:7 doi:10.1186/1742-4690-8-7
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BioMed Central: 3 citations
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Leukotrienes inhibit early stages of HIV-1 infection in monocyte-derived microglia-like cells Jonathan Bertin, Corinne Barat, Dave Bélanger, Michel J Tremblay Journal of Neuroinflammation 2012, 9:55 (16 March 2012) |
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Mutations affecting interaction of integrase with TNPO3 do not prevent HIV-1 cDNA nuclear import Alexandra Cribier, Emmanuel Ségéral, Olivier Delelis, Vincent Parissi, Aurélie Simon, Marc Ruff, Richard Benarous, Stéphane Emiliani Retrovirology 2011, 8:104 (16 December 2011) The functional analysis of HIV-1 IN mutants reveals distinct structural basis for TNPO3 interaction and suggests that the interaction between IN and TNPO3 is not a major determinant of nuclear import but could take place at a nuclear step prior to integration.
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Research
Candela Iglesias, Mathieu Ringeard, Francesca Di Nunzio, Juliette Fernandez, Raphael Gaudin, Philippe Souque, Pierre Charneau, Nathalie Arhel Retrovirology 2011, 8:92 (10 November 2011) This work establishes that the central DNA Flap is required for HIV-1 spreading infection but points to a residual DNA Flap independent nuclear import, whose functional significance remains unclear since it is not sufficient to support viral replication.
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