RNA interference: a multifaceted innate antiviral defense.
Kumar A.
The RNA interference mechanism utilizes short RNA duplexes to either suppress or induce target gene expression. Post-transcriptional regulation mediated by microRNA is an integral component of innate antiviral defense. The magnitude and the efficiency of viral restriction guided by RNA-based defenses, as well as the full physiological implication of host-pathogen engagement, constitute exciting areas of investigation in the biology of non-coding RNAs.
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PMID: 18241347 [PubMed - indexed for MEDLINE]PMCID: PMC2259359